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FIT.Y.E.R.O. (Meathead, wellness, fitness, diet, exercise) Thread

Really interesting The Genius Life podcast out today on GLP-1ā€™s. Yeah they discuss weight loss but the more interesting results they are finding is how lower doses improve cellular regeneration, specifically in the brain.

Currently thereā€™s a real world trial thatā€™s reached stage 3 looking at effects on GLP-1ā€™s on dementia and Alzheimerā€™s and results are showing a 53% lower risk of dementia, Alzheimerā€™s and type II diabetes. Though Iā€™m sure big pharma will find a way to bastardize this like they did with semaglutide : ozemptic :: tirzepatide : mounjaro.
It sort of pisses me off because I really don't want to take any medications, but what if this is truly something you should take to have a healthier life?
 
The data is leaning more and more to the GLP-1ā€™s being fantastic tools for overall health when microdosed on an ongoing basis. Itā€™s honestly kind of astonishing some of the things being discovered about themā€¦
 
Maybe I'm a cynic, but something that is supposed to be a miracle drug with no downsides that makes Big Pharma billions per month of reliable income just strikes me as something likely to be good to be true.
 
It sort of pisses me off because I really don't want to take any medications, but what if this is truly something you should take to have a healthier life?
Peptides are short-chain amino acids, not medicine. Nothing synthetic about them, they're naturally occurring in the body / our food, but over time we don't produce as much or process as efficiently.

They're the opposite of what Big Pharma is offering as peptides can't be patented. So Eli/Pfizer take semaglutide / tirzepatide and add their proprietary ingredients so they can patent the drug, and that is what many of us have warned against, along with dosage, diet and actually exercising vs. just taking the spike -> you don't know what makes up the new compound.
 
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Yeah, Hank, not to pile on, but generic peptides (of which GLP-1ā€™s are just one class) are the literal complete opposite of what Big Pharma wants. In fact, their lobbyists are behind the most recent push in which the FDA banned several of them. I know of anecdotal cases from friends with connections to the medical industry, and you can also find some interesting podcasts out there about the whole conspiratorial effort by Big Pharma to oust them.

The only way they can really capitalize on it is taking the original amino chain structures and changing them to some patented formula (e.g. Ozempic, Wegovy, Mounjaro, etc.), but the generic forms can be purchased easily and for fractions of the cost of the prescription shit. The generic forms also have less side effects (practically none in some cases; I have friends that have taken generic Semaglutide and literally didnā€™t experience a single thing other than the weight loss benefits).

People are starting to discover that, and Big Pharma is terrified by it.
 
Trust that several of us have done extensive research over multiple years on peptides and wouldn't be taking them or recommending them (to my mother of all people, after she had major surgery) if we didn't know the pro's & con's, or were affiliated and distributed by Big Pharma. Which, next to journalists, are a plague on the planet.
 
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Trust that several of us have done extensive research over multiple years on peptides and wouldn't be taking them or recommending them (to my mother of all people, after she had major surgery) if we didn't know the pro's & con's, or were affiliated and distributed by Big Pharma. Which, next to journalists, are a plague on the planet.
Hey Bonzo - I might be missing something here - where can I get peptides? I thought this was the Ozempic stuff? Is there a non script option you recommend?
 
As CSC said, those Big Pharma brands take the peptide and add their proprietary blend so they can trademark. What we've always referenced is the naturally occurring peptide, not the drug.

Hit me up offline Wayne, as there's plenty of places to buy. The key is in everything else -> goals (add muscle, cut, heal, cognitive function) diet, dosage, time of dosage, workout routine, etc.
 
I hear about 15 commercials a day about GLP-1s you can order from him or hers.com but not sure if thatā€™s what weā€™re talking about
 
I hear about 15 commercials a day about GLP-1s you can order from him or hers.com but not sure if thatā€™s what weā€™re talking about
Yes, semaglutide and tirzepatide are GLP-1's.

Ozempic is a GLPā€‘1 analog with 94% sequence homology to human GLPā€‘1. That 6% is where they patent their compound and make it proprietary. Can't find Mounjaro's breakdown, but guessing it's similar to allow Lilly to patent.
 
On Friday evening a lightning strike next door knocked out our wifi. We didn't get it fixed until Saturday morning and didn't realize that the 8 Sleep hadn't turned back on Saturday night. My normally very kind, loving wife is currently a raging hellbeast of multiple nights of sleeplessness.

I'll donate plasma before I'll give this damn thing up. Word is bond.
 
She's lovely on vacation (and in general) but we do actually plan to not sleep as well when we are away from home. Unexpectedly going without the thing reinforced that.
 
At the suggestion of Anth and his iron overlord, switched up the programming to full body workouts with the theory being less is more at this age, rather than annihilating a muscle group and taking days to recover.

First time in 20 years of lifting to give this a try and two days in, change-of-pace is welcomed. Feel like it'll take some getting used to, as in one sense you can push it for each muscle group and feel fresher, but with only one of legs, chest, back, shoulders, tri or bi, you don't get into a groove or a massive pump.

Gonna give this a 6 week run then reassess.
 
Still eating clean. Feel good. Gut health is definitely improved. No need for kombucha or late night Tums. My weight loss has kinda plateaued, however. Keepin at it and still enjoying an evening cigar (3 a week).

Changed up my supplements. Thorne Menā€™s +50 supplement, Magnesium Citrate, L-Argenine Plus, Creatine, all added to my B12, D, Zinc regimen. No more ā€˜Frank Thomas Boner Pillsā€™ (Nugenix Total T). Wife heard me once mention it by the nickname, and balked at reordering.

Grilled Chicken kebabs, Taziki, Cucumber salad meal prep was easy and completely healthy. Doing the same with lamb next.
 
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Grilled Chicken kebabs, Taziki, Cucumber salad meal prep was easy and completely healthy. Doing the same with lamb next.

Made lamb kabobs last night with homemade Tzatziki:
  • 2 lb ground lamb
  • 1/2 cup Italian parsley
  • 1/4 cup grated red onion
  • 6 cloves chopped garlic
  • 2 tsp cumin
  • 1.5 tsp salt
  • 1.5 tsp cardamom
Mix all that up, put it on skewers, grill. Delicious.

Bulked up over the last 12 months - gained 30 lbs but clearly it was all muscle as my bench, squat and dead lift went way up. J/K - it was a ton of fat too. Man, talk about that sneaking up on you. I basically kept my diet the same, but added protein shakes, and did less cardio. Rough back of the envelop math in terms of increased calories / reduced calorie burn = the 105K extra calories that got me to where I was. Sad!

Started to address this in July re: working out more. Made 0 difference in terms of weight.

Started food tracking in August. Made a huge difference. Also ran 100 miles last month on top of lifting.
 
Question that comes to mind when I see all the talk about high protein (non-keto) diets. How do you effectively maintain a calorie deficit if you are eating your weight in protein grams (or more)? Most people only have time to work out an hour or so per day...
 
Question that comes to mind when I see all the talk about high protein (non-keto) diets. How do you effectively maintain a calorie deficit if you are eating your weight in protein grams (or more)? Most people only have time to work out an hour or so per day...
This 7.5 oz chicken breast I'm eating is 350 calories and 66 grams of protein. Eat that 3x and I've hit my bodyweight in protein at just over 1k calories.

If you get your protein from quality sources, you don't have to eat massive amounts to reach your bodyweight or more and be in a deficit. Your carb intake is what will determine your caloric surplus or deficit.
 
I have added a 4th burnout set and a full new exercise per workout. Huffing and puffing, keeping HR above 115 for entire session.

<~~~~ sick of hard-boiled eggs.

Avocados and salads that are great for you, but the associated oil is jammed packed with caloriesā€¦ sneaky bastards.
 
NOT ALWAYS TRUE: After doing a little baseline meal tracking, ya boy Wayne Dougan was GREAT at getting way too many calories from fat.
True, should have added fats as the other variable to determine + / -.

Point being in addressing Dore's question about protein & bodyweight, whole food sources has way less caloric impact on your daily intake as carbs and fat.
 
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Still eating clean. Feel good. Gut health is definitely improved. No need for kombucha or late night Tums. My weight loss has kinda plateaued, however. Keepin at it and still enjoying an evening cigar (3 a week).

Changed up my supplements. Thorne Menā€™s +50 supplement, Magnesium Citrate, L-Argenine Plus, Creatine, all added to my B12, D, Zinc regimen. No more ā€˜Frank Thomas Boner Pillsā€™ (Nugenix Total T). Wife heard me once mention it by the nickname, and balked at reordering.

Grilled Chicken kebabs, Taziki, Cucumber salad meal prep was easy and completely healthy. Doing the same with lamb next.
Believe the conventional wisdom says you need to bump calories for a bit as your body has adjusted to the stress of being undernourished. Then you should be able to go on another cut after a few weeks of reverse diet.
 
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-Was sick as a dog last week. Whoop was not pleased with my increased body temp, RHR, and Resp Rate. Geez, coughing, sweating, fever, headache mess. Lungs are still a mess but closer to 90%. Had the 8 sleep on 62 degrees and still sweating through it.

-I had been thinking about full body workout because I needed a break from M- Back/Sho, Wed - Legs, Fri - Chest/Tri, Sat - Bis/Sho. I always loved full body.

-Being sick helped kick start the cut. ate clean af all week, very little booze intake. Ready to roll. Just need my lungs back.
 
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Six days of seminars last week has me at my highest ever weight: 220. Proud of myself for not touching the piles of candy available all week and limiting desserts. However sitting for a week is awful.

Happy to get onto a proper meal plan once I finish eating my way through these ribs that were dropped off over the weekend. Plus looking forward to making use of my new pickup, a Rhino belt squat. Just need to get it from my brotherā€™s garage in NKY to Knoxville.šŸ«¤
 
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Kooky fallin' off the wagon!
IMG-4342.jpg


Some famous TikTok peasan who throws mozz was here. He whipped a few balls my direction. Delish
 
- life is too short to forgo all delicious food that happens to cause Chonkening. Moderation atkot.

- I wish I was one of those women who could keep up 4-5 days a week of workouts through pregnancy, but I ain't. And that's okay. Baby boy is getting big. Pretty much feel like I'm walking around with a basketball strapped to me at 29 weeks. My obliques are hanging on for dear life. Box squats and sumo deadlifts still feel pretty damn good, but things like tying my shoes or rising from the couch? GTFO. Wheezy F Baby over here.

- Have to admit I'm getting pretty pumped about the light at the end of the tunnel now that I'm in third tri. I know plenty can happen in delivery that could significantly complicate my recovery and the resumption of my normal fitness routine (not to mention a newborn), but now that there's a delivery date looming, I can actually contemplate an actual return. I had to scale back training after my last meet in August 2022 because I had to stop the fun vitamins for a bit before we started trying, then it took a year to conceive, and now I'm large marge growing this baby. I am very much looking forward to Return of the Mack Pretzel, whatever that looks like post-partum. I have a couple goals in mind by kid's first birthday, but I'm not getting too attached to those just yet. I don't know if I'll logistically be able to compete again, but I feel optimistic about being physically able to do it, and that's huge. In the meantime, trying to stay grounded in keeping up sufficient fitness/mobility to try to facilitate a smooth-ish delivery, at least as much as one can. Hopefully I can just yeet this baby right out when he's ready. Fingers crossed.
 
Pretty sure you're doing a loaded carry 24/7 at current, pretzel.

@anthonys735 and other whoop users, have you tried using the strength training function? Anyone have a good guide for how to become an advanced user of it?

With the 8 Sleep's biometric tracking, I'm trying to figure out whether I should keep the Whoop. We have a Concept2 rower and use it for a couple of months every winter. This year I want to use the Whoop to try to improve my cardio as much as possible during that time. Kind of excited about it, to be honest. At 43, I'm getting to the age where if I don't get really focused, I will never see another true PR again. Might as well get the ticker in tip-top shape now that I've lost some weight and added some muscle.

However, between now and then, I'm planning on just doing some version of lifting and walking. I currently use Whoop to track my walks (mainly just to make sure I alway stay at 3 mph or greater and to track weekly and monthly mileage) and as a general diagnostic tool. I'd like to get more out of it if I can.
 
With my entire chest, **** THAT. IUD is going in as soon as doc will put it there post-delivery. We went into this being 95% sure on one-and-done and being elbow deep in it now...I don't think I'm up for this again. I'll be 36 when I deliver, husband is 39, so time wasn't on our side when we started trying. My body needs time to heal and I really don't like the escalating odds of genetic issues that come with rising age. Lil dude will have plenty of "cousins" (no PTI, but kinda) around his age to play with. Obv we could change our minds, hence IUD instead of tubal (and husband has volunteered for vasectomy when we're sure), but I can't think of anything that sounds more awful than being pregnant and having an infant lol
 
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