Mounjaro/Ozempic weight loss

[Caveman Catfan]

Awesome guess we need to modify this thread title just gotta find a doctor to script me

FDA approves Eli Lilly’s Zepbound, a weight loss drug similar to Ozempic and Wegovy

Some analysts predict the weekly injectable medication could become the best-selling drug of all time.

www.nbcnews.com

“In a phase 3 clinical trial, Zepbound led to an average weight loss of 22.5% body weight, or about 52 pounds, surpassing all currently available weight loss medications on the market. The participants in the study had obesity or were overweight with at least one weight-related condition.”

Wow! This could be life changing for some obese people.

 

[roguemocha]

“In a phase 3 clinical trial, Zepbound led to an average weight loss of 22.5% body weight, or about 52 pounds, surpassing all currently available weight loss medications on the market. The participants in the study had obesity or were overweight with at least one weight-related condition.”

Wow! This could be life changing for some obese people.

So would a healthy diet and exercise. 🙄

 

[Wesley91581]

That Drug = $13K/year

Gym Membership = $240/year
Walking Outside = Free

What a deal!

Ok so 240 a year is like planet fitness or crunch - we know people use LAC /YMCA /LA fitness etc. which are triple that - furthermore outside of mostly college kids most gym memberships are used only in Jan/feb and mostly wasted the other 10 months of the year.

 

[Freetaxreturn]

Ingenious move by Lilly, same active molecule ingredient as Mounjaro but labeled as a separate drug. Reminds me of Wellbutrin and Zyban, both same product but with different patent lives. Bravo Lilly 🍺

 

[BeaveUKGT]

LOL at the name Zepbound. There are lots of stupid names for recent medications, but this one is exceptionally bad.

 

[Hank Camacho]

Wow! This could be life changing for some obese people.

So could a GD walk.

 

[anthonys735]

LOL at the name Zepbound. There are lots of stupid names for recent medications, but this one is exceptionally bad.

Wegovy? I'm sure they poured millions into focus groups analyzing a name that sounds like toddler gibberish.

 

[WayneDougan]

Wegovy? I'm sure they poured millions into focus groups analyzing a name that sounds like toddler gibberish.

They could call it "Take this you fat bitch" and people would take it at the same levels. It's a wonder drug.

 

[roguemocha]

I’m absolutely fat and lazy shaming people in this thread, but I’d so much like for everyone to get healthier and in better shape, feel better physically and mentally.

The problem is so many in here have made it clear they don’t want to lift a mfing finger to help themselves, they just want a shot because they’re f**king lazy pussies. The same reason you just want to take a shot and not work for it is the same reason you got fat and obese in the first place, you don’t want to help yourself.

It would be so much more rewarding and you’d be in way better shape if you worked for it. I GUARANTEE some of those same people are telling their kids that they need to put their head down, work hard, earn it (whether it’s sports, grades whatever) yet when it comes to them they don’t want to do that. Why not just dive your 14 year old baseball player steroids while you’re at it, same touching thing man.

You ALL KNOW you’re being lazy and begging for instant gratification, all things you try and keep your kids from being.

If anyone thinks there is a miracle drug without serious side effects that does this, you’re wrong.

 

[Caveman Catfan]

🙄

I have not read this full thread, @roguemocha @Hank Camacho. Are people bad talking walking and healthy living? Why so fired up?

The idea that some obese people who have not had success with gym memberships and changing lifestyles should not be able to lose weight via a medication and attempt to get a healthier habitus, even if not the ideal, is kind of weird.

Maybe losing that weight is the motivation they need to change their habits.

 

[Wesley91581]

I’m absolutely fat and lazy shaming people in this thread, but I’d so much like for everyone to get healthier and in better shape, feel better physically and mentally.

The problem is so many in here have made it clear they don’t want to lift a mfing finger to help themselves, they just want a shot because they’re f**king lazy pussies. The same reason you just want to take a shot and not work for it is the same reason you got fat and obese in the first place, you don’t want to help yourself.

It would be so much more rewarding and you’d be in way better shape if you worked for it. I GUARANTEE some of those same people are telling their kids that they need to put their head down, work hard, earn it (whether it’s sports, grades whatever) yet when it comes to them they don’t want to do that. Why not just dive your 14 year old baseball player steroids while you’re at it, same touching thing man.

You ALL KNOW you’re being lazy and begging for instant gratification, all things you try and keep your kids from being.

If anyone thinks there is a miracle drug without serious side effects that does this, you’re wrong.

3 things

1. Have you ever thought about working in sales or as a motivation speaker?

2. Not every case but some people have bad genetics that they can’t overcome

3. Whatever the case it comes down to a lifestyle change - some people may do xyz like you said above and drop some weight but to maintain that requires a permanent lifestyle change and not everyone can and will do that

 

[roguemocha]

1. My life is a motivational speech bruh.

2. Bad genetics can be overcome. My genetics are to be super skinny and very difficult to put on weight, yet here I am after 15-20 years of hard work #60 bigger than anyone in my family.

And to your point, bad genetics usually mean one thing, that family for years has eaten like dogshit and continue the cycle by feeding their kids absolute dogshit and not encouraging outdoor activities and sports.

My genetics also push me toward being an alcoholic but I fight that shit every day. It’s hard, it sucks and the easiest thing to do is grab a bottle and chill on the couch but I don’t.

3. If they’re not willing to put the work in, they don’t really deserve it. That’s my opinion anyway. I hated my nursing school classes but I did them anyway because I had a goal.

Comfort is a slow death, prefer pain. You don’t grow in any aspect in comfort.

There aren’t many “great” memorable people in history that didn’t go through a ton of pain and suffering at some point.

 

[anthonys735]

3 things

2. Not every case but some people have bad genetics that they can’t overcome

 

[Hank Camacho]

Ozempic, etc just strike me as analogous to methadone or suboxone. Rather than address the behaviors causing obesity, we are just throwing drugs at people. Those drugs are all but guaranteed to have dramatic side effects that will likely be catastrophic long term.

The obesity crisis in America is solely caused by behavior. It is entirely too easy to not move and consume metric tons of cheap carbohydrates. Our poor people are fat! That never happened in human history until we got so rich, there are no limits on sloth.

 

[roguemocha]

Great analogy.

“I still want to get high but I like it free from the government and called something else so I feel better about it. I don’t want to change my life at all, just throw pills at me.”

No different at all than these people on here saying, “I tried one time for a month to exercise 3 days/week for 30 mins and not eat fast food 6 days/week but it was hard. So instead of walking every morning before work and afternoon after work or hitting the gym, can’t you all just throw pills at me? Life is hard and I don’t want to give any effort but I do want results…”

That’s a loser mentality and these people saying you can’t overcome genetics have a loser mentality as well propped up by the govt and big pharma telling them they’re right, it’s not their fault, why try you’ll never overcome your genetics like that GD 60 minutes interview that was a total farce.

Hooker worked for a company that sold that shit and they never told anyone or didn’t do any vetting or 60 Minutes was in on it. That interview literally told people if you have bad genetics there’s nothing you can do so don’t try and just take the meds.

 

[Ron Mehico]

If it’s going to result in the obese being less so, and cut down on all the issues (health costs, etc) that normal people have to incur, then I’m all for it. Ironically, if it works as intended, it will harm other pharmaceutical companies (less need for cholesterol and BP meds, less diabetes etc).

What I’m concerned about is this is yet another scam by big pharma where this “miracle” drug will result in severe side effects and an even bigger clusterf*ck than we have now. I guess time will tell because there’s no stopping this train.

 

[anthonys735]

We've been over it several times in the thread. If it's used as a catalyst to change... I see no issue with it. The benefits probably outweigh the side effects. But if you're gonna take the sh*t, still eat like a slob, refuse to do any type of physical activity, and just melt away your vital systems... it's gotta be worse than being obese. Same if you're a soccer mom with a few extra lbs, starving yourself isn't the way to go about it. I don't think turning people to goo inside is going to be a long term win for the health care system.

Genetics play a part but there's none you can't overcome(within reason).

Wish it was required to maintain the scrip only by consulting monthly with a dietician and physical trainer for evaluation. Maybe using an activity tracker or something.

 

[roguemocha]

Agreed @Ron Mehico but for cholesterol they’ll just continue to fudge numbers and lower the WNL numbers.

Diabetes is scheduled to take over as the #1 healthcare cost soon and it’s insane how much it costs.

“The Economic Report, which is published every five years, found that the total annual cost of diabetes in 2022 is $412.9 billion, including $306.6 billion in direct medical costs and $106.3 billion in indirect costs.”

Obesity and laziness is costing us half a trillion dollars you fats. Get it together please!

 

[Bill - Shy Cat]

. Same if you're a soccer mom with a few extra lbs, starving yourself isn't the way to go about it.
Wish it was required to maintain the scrip only by consulting monthly with a dietician and physical trainer for evaluation. Maybe using an activity tracker or something.

Agree 100%. The way I understand it, if you cut calories and don’t combine with restistance training, you lose muscle and fat. The loss of muscle just sets you up for future problems.

 

[anthonys735]

Agree 100%. The way I understand it, if you cut calories and don’t combine with restistance training, you lose muscle and fat. The loss of muscle just sets you up for future problems.

Actually, from what I've seen they're losing muscle and bone density at a higher rate than fat. Also affecting vital organs. Hence the hair loss, empty looking ozyempic face, and bowl issues. Fat is typically the last thing to go when you're malnourished.

 

[Freetaxreturn]

Eli Lilly Shares Hit All-Time High After FDA Approves Drug for Weight-Loss Treatment

Eli Lilly shares hit an all-time high after receiving FDA approval for Zepbound, an injectable treatment to help people lose weight.

www.investopedia.com

Told you guys to jump on the train about 10 months ago 🔒

 

[Wesley91581]

We've been over it several times in the thread. If it's used as a catalyst to change... I see no issue with it. The benefits probably outweigh the side effects. But if you're gonna take the sh*t, still eat like a slob, refuse to do any type of physical activity, and just melt away your vital systems... it's gotta be worse than being obese. Same if you're a soccer mom with a few extra lbs, starving yourself isn't the way to go about it. I don't think turning people to goo inside is going to be a long term win for the health care system.

Genetics play a part but there's none you can't overcome(within reason).

Wish it was required to maintain the scrip only by consulting monthly with a dietician and physical trainer for evaluation. Maybe using an activity tracker or something.

Sadly if doctors are getting a cut of the scripts they offer it’s a non-starter but then again who will supply and pay for the millions of these devices that would be required? Also someone could say their numbers are skewed because “they left it at home on Monday”.

I think someone else mentioned it but yes this affects everyone since if your employer has a high number of medical costs/doc visits/etc it affects the employee premiums.

 

[anthonys735]

JFC. What do you mean who's gonna pay for them? The person that can't stop shoving bear claws down his gullet if he wants the magic potion. MyFitnessPal and Apple/Samsung Health are all free apps on your goddamn phone. They track calories, steps, or activities. Or if you want a decent wrist based step counter it's like $20-30. Maybe start there rather than injecting yourself with a drug.

 

[ukalum01]

The horse is just out of the barn at this point. We've been throwing pills at symptoms versus trying to fix actual healthcare problems for decades now... not sure why throwing these pills bothers people anymore than calcium blockers, blood pressure medicines, heart medications, type 2 diabetes medications, "thyroid" pills, Lipitor, cholesterol medicines, etc (which are all prescribed along with healthy diet/exercise).

 

[roguemocha]

Sadly if doctors are getting a cut of the scripts they offer it’s a non-starter but then again who will supply and pay for the millions of these devices that would be required? Also someone could say their numbers are skewed because “they left it at home on Monday”.

I think someone else mentioned it but yes this affects everyone since if your employer has a high number of medical costs/doc visits/etc it affects the employee premiums.

Yeah I don’t see businesses paying for your fat loss injections. Wouldn’t most insurance companies consider that a pre-existing condition or an elective procedure?

@ukalum01 they don’t prescribe healthy diet and exercise. They may mention it but they don’t tell you an in-depth way to go about it. They want to throw pills at you and get back to their office.

They may show you a picture of the food pyramid which is also total BS that was bought and paid for decades ago by food companies and no one has really bothered to change it or correct it.

My last PCP in Lex said my cholesterol was high(normal being on TRT) and asked if I wanted statins. I literally laughed out loud and said no, I’ll change my diet first (which I did and it’s normal again).

His reply was literally well if you take a statin you don’t have to change anything. <—That’s the mfing problem right there. If you offer that, lazy people are going to take the pill.

 

[Mossip]

So just through some cursory reading: this stuff doesn’t discriminate where the weight comes off because it basically creates extreme caloric deficits day after day? Can you force yourself to eat more to get into safer weight loss pacing/less extreme calorie deficits? Or is something else at play that this layman isn’t comprehending?

Regardless, when you start shedding lean mass, you’re basically lowering your resting metabolic rate, so when and if you ever stop taking it, not only will your appetite return, you’ll be in caloric surplus with much less food. Sounds like a health disaster.

 

[anthonys735]

So just through some cursory reading: this stuff doesn’t discriminate where the weight comes off because it basically creates extreme caloric deficits day after day? Can you force yourself to eat more to get into safer weight loss pacing/less extreme calorie deficits? Or is something else at play that this layman isn’t comprehending?

Regardless, when you start shedding lean mass, you’re basically lowering your resting metabolic rate, so when and if you ever stop taking it, not only will your appetite return, you’ll be in caloric surplus with much less food. Sounds like a health disaster.

That's all correct. From my understanding, you feel satiated most of the time, and the people that come off of it gain the weight back immediately.

I would assume the play would be to take it with a reasonable beginners fitness plan and a well balanced diet centered around protein intake. That way you're losing weight and building healthy habits.

 

[WayneDougan]

I am not judging at all and I’m not even about to take this drug even though my weakness is food, but an observation I’ve seen is that the guys who are the most disciplined about working out (anth, rogue, pti) are the most upset about this drug.

Guys, the "be more disciplined" thing clearly isn't working for most of the population and never will. The people who take this drug won't be jacked, fit, etc., but they'll look and feel better. Just enjoy the fewer fat people out there and relax.

 

[anthonys735]

I am not judging at all and I’m not even about to take this drug even though my weakness is food, but an observation I’ve seen is that the guys who are the most disciplined about working out (anth, rogue, pti) are the most upset about this drug.

Guys, the "be more disciplined" thing clearly isn't working for most of the population and never will. The people who take this drug won't be jacked, fit, etc., but they'll look and feel better. Just enjoy the fewer fat people out there and relax.

Yeah, I just don't get that attitude. Let's take this drug forever, that we know is melting our insides, to loose some weight, but not even consider a healthier diet, or fitness to accompany it. I guess you get that with statins, BP meds, and A1C to some extent but that's just kind of wild to me. I struggle with diet as well. If I didn't my BF would be <10% with the way I workout. It's tough to do. My frustration is with people just being like, "yeah I'm not even thinking of working out, it's genetic I can't do anything about it, and I eat sausage gravy everyday!!"

I will say, it's not everyone. I follow a couple of fitness pages on FB where people are using them in sequence with diet and exercise and having great success.

 

[roguemocha]

I am not judging at all and I’m not even about to take this drug even though my weakness is food, but an observation I’ve seen is that the guys who are the most disciplined about working out (anth, rogue, pti) are the most upset about this drug.

Guys, the "be more disciplined" thing clearly isn't working for most of the population and never will. The people who take this drug won't be jacked, fit, etc., but they'll look and feel better. Just enjoy the fewer fat people out there and relax.

It’s not about tomorrow Wayne, it’s about what happens in 10 years or whatever and they need 3 organ transplants and now hate their life because they’re not fat but lethargic, sunken face, body is operating at 60% because it doesn’t have enough cals or nutrients to maintain homeostasis and properly function.

Then these same people will say, “I NEED A NEW LIVER CANT SOMEONE JUST CREATE ONE IN A LAB AND GIVE IT TO ME?!?!?!”

And anyone can be more disciplined, that’s the upsetting part, they just don’t want to. It’s no different than millennials or whoever thinking they shouldn’t have to work shitty jobs out of college or should make 100K in their first job. No bitch, you have to put in some time if you really want something.

 

[Wesley91581]

That's all correct. From my understanding, you feel satiated most of the time, and the people that come off of it gain the weight back immediately.

I would assume the play would be to take it with a reasonable beginners fitness plan and a well balanced diet centered around protein intake. That way you're losing weight and building healthy habits.

Good luck

 

[roguemocha]

Good luck

Are you typing while looking in a mirror Wes?

 

[Wesley91581]

Bunch of stereotyping here about obese people but whatever everyone is judgmental about something they don’t like or agree thus the strong arming their opinion on others
Seems like some yall need a walk or anger management but I’m gonna go to Cracker Barrel for lunch

 

[anthonys735]

Lol, there's no stereotypes. Those are quotes from people in this very thread.

 

[roguemocha]

The truth can hurt sometimes Wes, we’re not your mother. We’re just stating facts you don’t like.

You and others have literally said you’re going to do nothing but take the injection because you don’t want to try.

I would say any of this to an obese person’s face if they asked me. You don’t have cancer bro, you overeat the wrong foods and don’t exercise. There’s a huge difference bubba.

I’m going to hop in the sauna and cold tub real quick while you go eat 100g of fat and carbs at the Barrel. I’ll bet I feel way better after than you do.

 

[Wesley91581]

The truth can hurt sometimes Wes, we’re not your mother. We’re just stating facts you don’t like.

You and others have literally said you’re going to do nothing but take the injection because you don’t want to try.

I would say any of this to an obese person’s face if they asked me. You don’t have cancer bro, you overeat the wrong foods and don’t exercise. There’s a huge difference bubba.

I’m going to hop in the sauna and cold tub real quick while you go eat 100g of fat and carbs at the Barrel. I’ll bet I feel way better after than you do.

All good - I’ve been fat shamed my whole life so nothing a discriminatory person says would bother me.

 

[Ron Mehico]

I do think there is a psychological/mental issue with the obese as well. Just as there is for drug addicts. It is a food addiction and psychological addiction in some capacity.

 

[Wesley91581]

The truth can hurt sometimes Wes, we’re not your mother. We’re just stating facts you don’t like.

You and others have literally said you’re going to do nothing but take the injection because you don’t want to try.

I would say any of this to an obese person’s face if they asked me. You don’t have cancer bro, you overeat the wrong foods and don’t exercise. There’s a huge difference bubba.

I’m going to hop in the sauna and cold tub real quick while you go eat 100g of fat and carbs at the Barrel. I’ll bet I feel way better after than you do.

Idk man those biscuits and gravy hit different but enjoy your protein powder and living a miserable life at 90.

 

[Freetaxreturn]

Bunch of stereotyping here about obese people but whatever everyone is judgmental about something they don’t like or agree thus the strong arming their opinion on others
Seems like some yall need a walk or anger management but I’m gonna go to Cracker Barrel for lunch

91581 I’m on my way, will you preorder me two bowls of sausage gravy ? I’ll buy 🍺

 

[Hank Camacho]

Bunch of stereotyping here about obese people

Whatever, dude. I love BBW porn.