Not that I agree with analytics all the time, but numbers suggest that is the correct way to play by limiting the chances of a team coming back. The thing is even if you win those games it isn't quite as "entertaining" to watch thus they are not as memorable. However if you do lose then everyone remembers. Especially if it's the last game that ends your season.
As I said I don't necessarily agree with this strategy, but the numbers usually pan out. I'm of the thinking if you're the better team (which if you build a lead you should say you are) you continue to play the way that got you the lead. Now in certain situations, losing a player to an injury or foul trouble changes my thinking a little.
The big difference in Calipari and Pitino philosophies is Cal usually doesn't want to embarrass another team (especially most of the conference teams) where Pitino would love to win by 100. That is the only thing about Pitino I miss. Certainly not in crucial late game adjustments as evidenced by his 1 win ('95 SEC Final vs Arkansas) in overtime games at UK against 8 or 9 losses, which included the '92 Elite Eight game vs the school we don't mention, '93 FF vs Michigan and '97 in the NCAA Championship to Arizona in his final game at UK.