| Opponent | 2024-25 Record | Postseason | Final NET Ranking | Final Ranking (AP/Coaches) | KenPom.com Final Ranking | Series History | Last Meeting |
| Bellarmine | 5-26 | N/A | 351 | NR/NR | 347 | UK, 1-0 | UK won, 60-41, on Nov. 29, 2022 |
| Georgetown (exhibition) | 18-16 | College Crown Second Round | 88 | NR/NR | 90 | ____ | ____ |
| Gonzaga | 26-9 | NCAA Second Round | 8 | 23/20 | 8 | Tied, 2-2 | UK won, 90-89OT, on Dec. 7, 2024 |
| Indiana | 19-13 | N/A | 54 | NR/NR | 45 | UK, 32-25 | IU won, 73-67, on March 19, 2016 |
| Loyola University Md. | 12-19 | N/A | 308 | NR/NR | 305 | UK, 1-0 | UK won, 87-63, on Dec. 22, 2011 |
| Louisville | 27-8 | NCAA First Round | 24 | 21/21 | 28 | UK, 40-17 | UK won, 93-85, on Dec. 14, 2024 |
| Michigan State | 30-7 | NCAA Elite Eight | 11 | 7/7 | 7 | UK, 14-12 | MSU won, 86-772OT, on Nov. 15, 2022 |
| North Carolina Central | 14-19 | N/A | 319 | NR/NR | 324 | Never met | First meeting |
| Purdue (exhibition) | 24-12 | NCAA Sweet 16 | 19 | 14/12 | 15 | ___ | ____ |
| St. John’s | 31-5 | NCAA Second Round | 13 | 11/10 | 14 | UK, 11-5 | UK won, 81-59, on Dec. 1, 2011 |
| Tennessee Tech | 15-17 | N/A | 292 | NR/NR | 303 | UK, 5-0 | UK won, 69-47, on Dec. 22, 2007 |
